Intravarsity — San Francisco, California

Synthetic Biology Designer

Synthetic Biology Designer: Engineer Genetic Circuits for a Biotech Startup. A 4–8 weeks Intravarsity career experience (30–50 hours) for school and undergrad

What if you could program living cells like computers? You'll work with a synthetic biology startup to design genetic circuits — toggle switches, oscillators, and biosensors — using computational modeling tools. Your designs follow iGEM standards and are evaluated by the startup's synthetic biologists.

Design genetic circuits and model engineered organisms using computational tools — working on the same synthetic biology principles used by biotech startups to create biosensors and biofuels.

Who it is for

High school, secondary school students & undergraduates. Basic biology knowledge helpful. Interest in engineering or biology.

Weekly plan

Week 1: DNA as Code

  • Meet the synbio startup team and tour their computational pipeline
  • Learn the central dogma and standardized genetic parts (BioBricks)
  • Explore the iGEM parts registry and study award-winning projects
  • Understand promoters, RBS, coding sequences, and terminators

Week 2: Circuit Design & Simulation

  • Design genetic toggle switches and oscillators in silico
  • Build mathematical models of gene regulatory networks in Python
  • Simulate circuit behavior and optimize parameters
  • Get feedback from the startup's synthetic biologists

Week 3: Application Design

  • Identify a real-world problem that synthetic biology can solve
  • Design a complete synthetic biology solution (biosensor, biofuel, therapeutic)
  • Create a detailed experimental plan with safety considerations
  • Address bioethics and dual-use concerns with the team

Week 4: iGEM-Style Presentation

  • Prepare an iGEM-style project presentation with all documentation
  • Write a project abstract and detailed proposal
  • Present to synthetic biologists and biotech investors
  • Receive Proof-of-Work credential and synbio recommendation

What you produce

  • Genetic circuit designs with simulation results
  • Synthetic biology project proposal
  • iGEM-style presentation
  • Synbio startup recommendation
  • Intravarsity Proof-of-Work credential

Skills

Molecular Biology, Genetic Circuit Design, Python Modeling, Synthetic Biology, Bioethics, Scientific Presentation, Experimental Design, iGEM Standards

Commitment

~5–8 hours/week for 4–8 weeks (30–50 hours total). 100% Virtual — work remotely with a Silicon Valley synbio startup.

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